รู้จัก 3 เทคโนโลยีที่ใช้ผลิตวัคซีนโควิด 19 – โพสต์ทูเดย์ สังคมทั่วไป

Learn about 3 technologies used to make the COVID 19 vaccine.

February 24, 2021 at 10:07 am

Medical experts explain three key technologies used in the manufacture of the COVID 19 vaccine. Point is safe. People who have already been infected can be vaccinated. Have adequate immunity

Prof. Dr. Viporn Wiprakasit, Department of Pediatrics. Medical Specialist in Molecular Medicine, Siriraj Hospital Mahidol University Medical School And National Distinguished Researcher of 2021 says there is now a huge amount of real and false information in the media about the COVID 19 vaccine. Causing Confusion in Society So let us understand the following

This is because COVID-19 uses “S-protein” to attach to human cells and infiltrate itself into the growth of the human body. The vaccination method is used. “Thistle” is the protein that is used to stimulate the immune cells to recognize and remember. When the real virus is found, immune cells destroy the virus that can invade. Prevent infection or when the infection is mild

There are currently three major production technologies for the COVID 19 vaccine:

1. mRNA technology Vaccination of the RNA genetic material that makes up the virus S protein But usually the viral genetic material has a protective cover. Without the shell, it is unstable and cannot stimulate immunity. So wrap the fat at the nano level, however, storage of this type of vaccine requires a very low temperature of minus 80 degrees Celsius, which is a very hot country. High temperature Storage is a challenge. Improper storage affects efficiency and safety. Pfizer and Modenar use this technology in their production.

2.Viral vector technology It is the invention of genetic DNA material to produce the S proteins of the coronavirus. And covered with a shell of another virus to be smuggled into the body, using the viral envelope of the genetic material, it can be stored at a temperature of around 4 degrees Celsius. Therefore, suitable for Thailand in hot weather.This technology has Russian companies Astrazeneca and Sputnik are used in vaccine production

3. Technology for deadly infections Can be achieved by actually bringing the virus with you To add more numbers And give the dead some substance No more pathogenic properties Then used to make the vaccine by adding immunostimulants This technology has long been used for rabies, polio and hepatitis -Vaccines used to make vaccines with this technology by Sinovac and Sinofarm companies from China.

Prof. Dr. Vipra continued The development of the vaccine safety is a top priority. With research at both the laboratory animal level, there are three stages of human research in mice and monkeys to investigate safety and efficacy. If it meets the World Health Organization criteria, it will be registered for use. Many countries around the world including Thailand approve it for emergency use. By confirming that people already infected can be vaccinated, they will have adequate immunity. Pain, swelling and fever after vaccination can occur with any vaccine. And confirm this with the updated information Using vaccines containing RNA and DNA did not affect any change in the human genetic code.

“The COVID-19 vaccination fits into the context of our country. And will start operations this week.It is an important measure. To make the people of Thailand and our country go through this crisis. “Prof. Said Dr. Vipra.